Flawed clinical practice guidelines may compromise patient care. Commercial conflicts of interest on panels that write treatment guidelines are particularly problematic, because panelists may have conflicting agendas that influence guideline recommendations. Historically, there has been no legal remedy for conflicts of interest on guidelines panels. However, in May 2008, the Attorney General of Connecticut concluded a ground-breaking antitrust investigation into the development of Lyme disease treatment guidelines by one of the largest medical societies in the United States, the Infectious Diseases (...) Society of America (IDSA). Although the investigation found significant flaws in the IDSA guidelines development process, the subsequent review of the guidelines mandated by the settlement was compromised by a lack of impartiality at various stages of the IDSA review process. This article will examine the interplay between the recent calls for guidelines reform, the ethical canons of medicine, and due process considerations under antitrust laws as they apply to the formulation of the IDSA Lyme disease treatment guidelines. The article will also discuss pitfalls in the implementation of the IDSA antitrust settlement that should be avoided in the future. (shrink)

Lyme disease is one of the most controversial illnesses in the history of medicine. In 2006 the Connecticut Attorney General launched an antitrust investigation into the Lyme guidelines development process of the Infectious Diseases Society of America (IDSA). In a recent settlement with IDSA, the Attorney General noted important commercial conflicts of interest and suppression of scientific evidence that had tainted the guidelines process. This paper explores two broad ethical themes that influenced the IDSA investigation. The first is the growing (...) problem of conflicts of interest among guidelines developers, and the second is the increasing centralisation of medical decisions by insurance companies, which use treatment guidelines as a means of controlling the practices of individual doctors and denying treatment for patients. The implications of the first-ever antitrust investigation of medical guidelines and the proposed model to remediate the tainted IDSA guidelines process are also discussed. (shrink)

P. M. Asaro: What should We Want from a Robot Ethic? G. Tamburrini: Robot Ethics: A View from the Philosophy of Science B. Becker: Social Robots - Emotional Agents: Some Remarks on Naturalizing Man-machine Interaction E. Datteri, G. Tamburrini: Ethical Reflections on Health Care Robotics P. Lin, G. Bekey, K. Abney: Robots in War: Issues of Risk and Ethics J. Altmann: Preventive Arms Control for Uninhabited Military Vehicles J. Weber: Robotic warfare, Human Rights & The Rhetorics of Ethical Machines T. (...) Nishida: Towards Robots with Good Will R. Capurro: Ethics and Robotics. (shrink)

Progressive supranuclear palsy is a movement disorder with prominent tau neuropathology. Brain diseases with abnormal tau deposits are called tauopathies, the most common of which is Alzheimer's disease. Environmental causes of tauopathies include repetitive head trauma associated with some sports. To identify common genetic variation contributing to risk for tauopathies, we carried out a genome-wide association study of 1,114 individuals with PSP and 3,247 controls followed by a second stage in which we genotyped 1,051 cases and 3,560 controls for the (...) stage 1 SNPs that yielded P ≤ 10-3. We found significant previously unidentified signals associated with PSP risk at STX6, EIF2AK3 and MOBP. We confirmed two independent variants in MAPT affecting risk for PSP, one of which influences MAPT brain expression. The genes implicated encode proteins for vesicle-membrane fusion at the Golgi-endosomal interface, for the endoplasmic reticulum unfolded protein response and for a myelin structural component. © 2011 Nature America, Inc. All rights reserved. (shrink)

In Eudemian Ethics I 6, Aristotle describes the progress of the ethical investigation as a drift from a) what is true but not clarifying to b) what is true and clarifying. The drift from a) to b) is usually interpreted as the overcome of a first obscure and confused grasp of the subject by a more accurate and reliable account. In this paper, I claim that the understanding of the methodological role of a) depends upon its dissociation from the notions (...) of obscurity and confusion. What is true but not clarifying should be rather understood as a first indistinct (but not confused) grasp of the subject. Its insuficiency as regards explanation is to be accounted on the base of its indistinctness and not on its supposed obscurity. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Plato's Doctrine of the Psyche as a Self-Moving Motion RAPHAEL DEMOS I WILLXSXTHEREADERto ignore for the time being what he has gleaned about the soul from the reading of the Phaedo and the Republic. In these dialogues Plato speaks of the soul sometimes as wholly rational, as having three parts, and so forth. But in these dialogues he is t~lklng of the human soul, which is a special (...) case, whereas in this essay I am de~Hng with the wider role and the concept of the soul as the efficient cause of motion, change, and all becoming everywhere in the cosmos. My cardinal texts in this exposition are the Sophist (246a-249d), the Phaedrus (245c, d), and a considerable portion of Laws, X. Consider the Phaedo, a dialogue with at least four motifs: it is a dramatic evocation of the last day in the life of Socrates, it is an argument for the immortality of the soul and for the reality of the world of ideas, it is a myth of the nether world, and finally, it is a theory of the cosmos as ruled by purpose--all in all, one of the great pieces of literature of the Western world. For the reader, it is an evocation of an attitude to life, based on Plato's conception of the soul--an attitude expressed in the famous phrase that the wise man spends his life meditating on death. As contrasted with what may be called his existential concern with the soul, in the other dialogues on which I will comment, Plato approaches the topic of the soul as part of his explanation of the cosmos. In these his attitude is objective and quasi-scientific. It is to this side of Plato's thought that I wish to call attention in this essay, where the establishment of the immortality of the soul is incidental to the more basic doctrine that the soul is an arche, a primary factor and an ontological principle. In the,Sophist, we find Plato playing the music of his philosophy in a new key. He refers to the "friends of the forms" as though he, himself, were an outsider looking in; then, too, he asserts that motion is really real in contrast to his derogatory references to motion in the Cratylus, the Phaedo, and the Republic.I In these (and other) dialogues, Plato contrasts change and changing things with the timeless forms in respect of reality: the former are said, at best, to be semi-real; only the latter are really real. But in the Sophist he changes his tune, arguing that total reality (~o ~v, to' ~a~rE~ By) includes both motion and rest (248e 8; 249d 3-4). What does he mean by these two words? That by 'rest' he means the realm of ideas is indicated (if not proved) by his references to the forms in the same context (247b 1But in the Theaeteius,he classifiesmotions in a semi-scientific fashion, leaving the impression on the reader that he regards motion as a reality. [133] 134 HISTORY OF PHILOSOPHY 1-2; 249b, 10, c 1).2 As for motion, Plato makes it clear that the term covers not only (a) physical motion but also (b) life, (c) psyche, and (d) phronesis or naus (249b 5). All these are said to be forms of kinesis; how this is so--how life, soul, mason may be described as motions or changes--is a matter for later comment. What is more to the point is Plato's insistence that motion and what is moved are onta (beings, 249b 2, d 3). Plato uses change (metabol$) interchangeably with kinesis; anticipating the Phaedrus, I will include activity under change. And anticipating the Laws, I will characterize some of this activity as mental; indeed the Sophist, includes within change nous, phronesis, and episteme; that is to say, understanding (in the sense of an activity, 249a, b, c).s Plato offers various reasons in support of his contention that change is real. He may also be offering a special demonstration as follows. The philosopher who denies that change is real is engaged in a mental activity, in short... (shrink)

The aims of this essay are (A) to examine the extent to which Marx, Engels and Lenin believed in revolution by peaceful means and what was their attitude towards the phenomenon of war, and (B) to reflect on the different interpretations of their writings, discerning between three schools of thought. It is argued that Marx and Engels considered violence only as an instrument of secondary importance and desirable insofar as there is no other alternative to change the system. It is (...) further contended that while they, in the course of years, adopted a more moderate position regarding the use of violence, Lenin's viewpoint radicalized as the possibility of a revolution in Russia became real. As years went by Lenin affirmed not only the use of violence but also the resort to terrorist activities. Unlike Marx and Engels he became an ardent supporter of all types of terror. (shrink)

The connective or can be treated as an inclusive disjunction or else as an exclusive disjunction. Although researchers are aware of this distinction, few have examined the conditions under which each interpretation should be anticipated. Based on linguistic-pragmatic analyses, we assume that interpretations are initially inclusive before either (a) remaining so, or (b) becoming exclusive by way of an implicature ( but not both ). We point to a class of situations that ought to predispose disjunctions to inclusive interpretations and (...) to situations that encourage exclusive interpretations. A disjunction's ultimate interpretation is based on its potential informativeness, where the interpretation of the disjunctive utterance having the smallest number of true conditions is considered most informative. Our investigation leads to five experiments employing arbitrary materials. Among the problems expected to encourage inclusive interpretations are those that present disjunctions in the antecedents of conditionals and in question forms. The best candidates to produce implicatures are those disjunctions that underdetermine an expected conjunctive conclusion, although other disjunctive utterances that are more informative as exclusive are discussed and tested. (shrink)

There exists a strong need for research in clinical sport psychology which does not merely gather information on prevalence rates for psychological disorders and case studies of affected athletes. Rather, research should also uncover the underlying psychological variables which increase the risk for depression and burnout in elite athletes. Many studies gather general factors (e.g. gender, injury, sport discipline) and stay on a more descriptive level. Both constructs (burnout and depression) are based on a temporal, stress-related process model assuming the (...) development of either syndrome results from unfavorable personal (e.g. dysfunctional attitudes, perfectionism, negative coping strategies) or environmental (e.g. cohesion) factors coexisting with severe stressors (i.e. chronic stress). Integrating this knowledge, we propose a shared model for depression and burnout in athletes: a sport specific diathesis-stress model. The present longitudinal study assesses data throughout one sporting season to analyze predictors for both constructs in junior elite athletes. Hierarchical multiple linear regression analyses resulted in six predictors for best model fit. The following factors demonstrated a significant impact on predicting (a) burnout or (b) depression scores at the end of the season: dysfunctional attitudes (a and b), coping strategies (a and b), perfectionism (a), recovery (b), stress (a) and the level of depression at onset (b). Variables such as cohesion or attributional style did not significantly predict depression or burnout. The study supports the structure of a process model (diathesis-stress model) for burnout and depression with the assumption of temporal progression. With some vulnerabilities and their temporal, developmental link identified, prevention can become athlete-specific, effective and economical. (shrink)

Since the introduction of the computer in the early 1950's, the investigation of artificial intelligence has followed three chief avenues: the discovery of self-organizing systems; the building of working models of human behavior, incorporating specific psychological theories; and the building of "heuristic" machines, without bias in favor of humanoid characteristics. While this work has used philosophical logic and its results may illustrate philosophical problems, the artificial intelligence program is by now an intricate, organized specialty. This book, therefore, has a quite (...) specialized audience of its own although it can be very valuable to those philosophers who are interested and competent in using this pioneering material. Five scientific papers report attempts to solve five different kinds of problems. Bertram Raphael describes an attempt to build a memory structure that converts the information input into a systematic model by "understanding" the informational statements as they are made. Daniel Bobrow's machine can set up algebraic equations from informal verbal statements. M. Ross Quillan asks: "What sort of representational format can permit the 'meanings' of words to be stored?" Thomas Evans' machine, Analogy, serves as a model for "pattern-recognition" rather than the "common-property" method of semantic memory. Fischer Black has developed a logical deduction mechanism for question-answering which keeps track of where we are and avoids endless deduction. The editor and John McCarthy contribute more general chapters, providing the historical background of cybernetics, and dealing with the problem of formalizing a concept of causality. Minsky ends the volume with his view that our convictions on dualism, consciousness, free will, and the like are used in the attempt to explain the complicated interactions between parts of our model of ourselves.--M. B. M. (shrink)

In his preface to Hobbes: Morals and Politics, Raphael tells us his intention is to provide "a genuine introduction for the student starting from scratch." That ought not deter others more familiar with Hobbes from reading the book. Raphael’s analysis is well-informed, sometimes insightful, and certainly worth reading. In addition to its intention to serve as an introduction, the book is also a vehicle for a rather elaborate interpretation of Hobbes’s theory of obligation. The interpretation of its (...) class='Hi'>Raphael in with the school of thought represented by Howard Warrender, F. S. McNeilly, et. al. (shrink)

This is the second edition of a very imaginative collection of readings in aesthetics from Plato to the present. In this second edition, seven selections have been deleted and fifteen new selections have been added to greatly enhance its usefulness to beginning students in aesthetics. Additional readings on artistic creation and drama have been provided and a number of illustrations of works by Raphael, Giotto, Matisse, Dürer, Brancusi, Henry Moore, et al. have been included this time to illustrate relevant (...) textual materials. As in the first edition, the author's primary intention is to establish the field of aesthetics as having the same integrity and adventuresomeness as other areas of philosophical inquiry and debate. With this goal in view, he has organized the readings around "certain sets of basic problems that still seem worth debating and attempting to solve." Each section is centered around specific problems and issues in aesthetics, beginning with the broadest question, "What is Art?," and moving on to such issues as the nature of the various art forms, the nature of tragedy, the problem of response to art and, finally, the nature and goal of art criticism. Various readers and teachers in aesthetics no doubt, will find fault with or gaps in his selections of readings. But laying aside such parochial matters as ideology and personal taste, this volume puts in the hands of the student of aesthetics a compendium of essays on the major issues and areas of concern in aesthetics which can easily be supplemented by use of a xerox machine. The editor has included such scholarly aids as a brief introduction to each section, interpretative and cross-referential footnotes and a minimal bibliography.--J. B. L. (shrink)

Johnson and Stricker published an opinion piece in the Journal of Medical Ethics presenting their perspective on the 2008 agreement between the Infectious Diseases Society of America (IDSA) and the Connecticut Attorney General with regard to the 2006 IDSA treatment guideline for Lyme disease. Their writings indicate that these authors hold unconventional views of a relatively common tick-transmitted bacterial infection caused by the spirochete Borrelia burgdorferi. Therefore, it should come as no surprise that their opinions would clash with the (...) IDSA's evidence-based guidelines for the diagnosis and treatment of Lyme disease. Their allegations of conflict of interest against the IDSA resemble those made against the National Institutes of Health, the Food and Drug Administration and the Centers for Disease Control and Prevention in 2000, which were found to be baseless. It is the responsibility of all physicians and medical scientists to stand up to antiscientific, baseless and unethical attacks on those who support an evidence-based approach to caring for patients. (shrink)

Although political theory was pronounced dead only a few short years ago, this collection of articles shows that much life is left in contemporary political theory. Based on a symposium concerning human rights held at the Sixth World Congress of the International Political Science Association held at Geneva in 1964, the collection includes papers by Macpherson, Polin, Chapman, Cranston, Raphael, Mayo, Schneider, and Fawcett. Macpherson and Polin set the context by exploring the concept of rights in Hobbes and Locke. (...) While the other papers have an eye on traditional discussions, they are also concerned with exploring what "rights" does and can mean in the contemporary world. The international gathering of authors brings together diverse points of view on the common problem of human rights.--R. J. B. (shrink)

L’ouvrage s’inscrit dans une tentative, inaugurée par les travaux de B. Bourgeois et F. Fischbach, de lire Hegel et Schelling à titre d’égalité en envisageant la philosophie post-kantienne non pas comme un progrès linéaire, mais comme champ de virtualités qui ont aujourd’hui un sens autant généalogique que conceptuel. L’auteur revient ainsi à un moment historico-philosophique où « sous la triple influence de Herder, de Kant et de la Révolution française », l’histoire devient « une question pr...

About a month after his 83rd birthday Raphael Robinson was almost wholly incapacitated by a massive stroke, and 8 weeks later, on January 27, 1995, he died of ensuing complications. Mathematics was his life. He was always working on problems—those brought to him in journals or by colleagues, and others that he invented. Just three days before his death he received word that a paper of his, originating in a published problem, was accepted for publication. His 64 publications spanned (...) a full 6 decades, and included significant papers on number theory, combinatorics, complex analysis, and geometry, in addition to logic and set theory.Robinson was born on November 2, 1911, in National City, California. He came to Berkeley to study mathematics, obtaining an A.B. in 1932, an M.A. in 1933, and his Ph.D. in December, 1934. His dissertation was in complex analysis. He took 12 graduate courses in a variety of fields, but not one was close to logic or set theory—which was later the setting of about a quarter of his publications.After completing his studies Robinson served as Instructor for two years at Brown University, then returned for good to Berkeley in 1937, reaching the rank of full Professor in 1949. He taught a great variety of courses and was known as an excellent teacher, but was most interested in problemsolving and research and in 1972, at age 61, he elected early retirement, at considerable financial sacrifice, in order to concentrate on these pursuits. (shrink)

Les écrits de Kant sur les races humaines, émaillés de caractérisations et de jugements qui heurtent notre sensibilité contemporaine, sont accueillis par un silence gêné des commentateurs. Ceux-ci croient bon de s'abstenir d'analyser ces textes, et d'y voir a priori des opinions mal élaborées, victimes de l'air du temps. Mais en évitant de se confronter à ce tabou, ils jouent aussi un mauvais tour à Kant. Car le lecteur peut avoir l'impression qu'on lui cache quelque chose. Qui plus est, les (...) textes sur les races font preuve d'une cohérence interne et d'une compacité théorique remarquables, et leur puissance explicative est inégalée dans le champ de l'anthropologie physique de son époque - celle de Buffon, de Blumenbach ou de Meiners. Est-ce à dire, comme le craignent d'avance les commentateurs, qu'on trouve chez Kant un authentique racisme théorique? En fait, cette accusation de racisme n'a pas vraiment d'objet à une époque où les modalités d'une pensée non raciste, c'est-à-dire d'une anthropologie non naturaliste, étaient au mieux en cours de constitution. Ce constat nous mène à considérer que seule une analyse dépassionnée des thèses raciologiques de Kant, prises dans toute leur violence, peut rendre justice à la doctrine kantienne. Nous ne cherchons pas à produire une " disculpation théorique " de Kant. Mais inversement, cet ouvrage ne vise pas non plus à formuler des thèses scandaleuses ou à révéler un " Kant non universaliste ". Il entend simplement montrer la tension d'une pensée qui fait de l'histoire un processus de civilisation en principe universel, articulé autour d'un centre de gravité à la fois géographique et spirituel, l'Europe, peuplée d'hommes blancs. Cet ouvrage intéressera les étudiants et chercheurs en philosophie et en histoire des sciences, mais aussi les étudiants et chercheurs en anthropologie. (shrink)

Climate change calls for resource saving, sustainable ways to generate energy as well as moderation in growth and industrialization. Religion can help to develop a general change in our worldview and a realignment of our aims and lifestyles. If we are seeking a new outlook on life, religion should be a part of it, as religion and culture shape and form our outlook in significant ways. Gordon Kaufman is one of those theologians who have early on openly acknowledged the scope (...) and responsibility of religion concerning environmental exploitation and destruction.1 Due to his dissatisfaction with traditional anthropomorphic talk about God and the world, Kaufman was always looking for new ways of shaping... (shrink)

This book is an enquiry into the concept of the 'self', transcending the barriers of 'non-self' and realizing the non-dual Consciousness within and without.

This chapter examines how the borderline cases pointed out by English naturalists and philosophers in the second half of the seventeenth-century call into doubt the common notion of life as a vegetative power. In the first part of this chapter, I focus on Nehemiah Grew’s notions of life and living beings by comparing his plant anatomy, in which he examines the cases of sponges and corals, with his physico-theology. In the second part, I confront Grew’s views on life to those (...) of John Ray and Ralph Cudworth. My aim is threefold. First, I want to show that there was then no agreement on what a “vital phenomenon” is. Second, I want to emphasize the fact that what we would classify today as physical phenomena, such as gravitation, were then regarded as living phenomena. Third, and accordingly, I would like to challenge the view that the English naturalists and philosophers who then developed a physico-theology simply used empirical vital phenomena in order to refute Descartes’ metaphysics. In my view, there were no such things as “empirical vital phenomena.” Indeed, the very identification and description of the phenomena considered as “vital” was a matter of interpretation, and those different authors did not share the same set of assumptions regarding what kinds of beings are alive. At the very least, they do not share the set of assumptions that define what we regard as “vital.”. (shrink)

In recent years, the scientific study of meditation and psychedelic drugs has seen remarkable developments. The increased focus on meditation in cognitive neuroscience has led to a cross-cultural classification of standard meditation styles validated by functional and structural neuroanatomical data. Meanwhile, the renaissance of psychedelic research has shed light on the neurophysiology of altered states of consciousness induced by classical psychedelics, such as psilocybin and LSD, whose effects are mainly mediated by agonism of serotonin receptors. Few attempts have been made (...) at bridging these two domains of inquiry, despite intriguing evidence of overlap between the phenomenology and neurophysiology of meditation practice and psychedelic states. In particular, many contemplative traditions explicitly aim at dissolving the sense of self by eliciting altered states of consciousness through meditation, while classical psychedelics are known to produce significant disruptions of self-consciousness, a phenomenon known as drug-induced ego dissolution. In this article, we discuss available evidence regarding convergences and differences between phenomenological and neurophysiological data on meditation practice and psychedelic drug-induced states, with a particular emphasis on alterations of self-experience. While both meditation and psychedelics may disrupt self-consciousness and underlying neural processes, we emphasize that neither meditation nor psychedelic states can be conceived as simple, uniform categories. Moreover, we suggest that there are important phenomenological differences even between conscious states described as experiences of self-loss. As a result, we propose that self-consciousness may be best construed as a multidimensional construct, and that “self-loss,” far from being an unequivocal phenomenon, can take several forms. Indeed, various aspects of self-consciousness, including narrative aspects linked to autobiographical memory, self-related thoughts and mental time travel, and embodied aspects rooted in multisensory processes, may be differently affected by psychedelics and meditation practices. Finally, we consider long-term outcomes of experiences of self-loss induced by meditation and psychedelics on individual traits and prosocial behavior. We call for caution regarding the problematic conflation of temporary states of self-loss with “selflessness” as a behavioral or social trait, although there is preliminary evidence that correlations between short-term experiences of self-loss and long-term trait alterations may exist. (shrink)

There is converging evidence that high doses of hallucinogenic drugs can produce significant alterations of self-experience, described as the dissolution of the sense of self and the loss of boundaries between self and world. This article discusses the relevance of this phenomenon, known as “drug-induced ego dissolution (DIED)”, for cognitive neuroscience, psychology and philosophy of mind. Data from self-report questionnaires suggest that three neuropharmacological classes of drugs can induce ego dissolution: classical psychedelics, dissociative anesthetics and agonists of the kappa opioid (...) receptor (KOR). While these substances act on different neurotransmitter receptors, they all produce strong subjective effects that can be compared to the symptoms of acute psychosis, including ego dissolution. It has been suggested that neuroimaging of DIED can indirectly shed light on the neural correlates of the self. While this line of inquiry is promising, its results must be interpreted with caution. First, neural correlates of ego dissolution might reveal the necessary neurophysiological conditions for the maintenance of the sense of self, but it is more doubtful that this method can reveal its minimally sufficient conditions. Second, it is necessary to define the relevant notion of self at play in the phenomenon of DIED. This article suggests that DIED consists in the disruption of subpersonal processes underlying the “minimal” or “embodied” self, i.e., the basic experience of being a self rooted in multimodal integration of self-related stimuli. This hypothesis is consistent with Bayesian models of phenomenal selfhood, according to which the subjective structure of conscious experience ultimately results from the optimization of predictions in perception and action. Finally, it is argued that DIED is also of particular interest for philosophy of mind. On the one hand, it challenges theories according to which consciousness always involves self-awareness. On the other hand, it suggests that ordinary conscious experience might involve a minimal kind of self-awareness rooted in multisensory processing, which is what appears to fade away during DIED. (shrink)

Many authors argue that conscious experience involves a sense of self or self-consciousness. According to the strongest version of this claim, there can be no selfless states of consciousness, namely states of consciousness that lack self-consciousness altogether. Disagreements about this claim are likely to remain merely verbal as long as the target notion of self-consciousness is not adequately specified. After distinguishing six notions of self-consciousness commonly discussed in the literature, I argue that none of the corresponding features is necessary for (...) consciousness, because there are states of consciousness in which each of them is plausibly missing. Such states can be said to be at least partially selfless, since they lack at least one of the ways in which one could be self-conscious. Furthermore, I argue that there is also preliminary empirical evidence that some states of consciousness lack all of these six putative forms of self-consciousness. Such states might be totally selfless, insofar as they lack all the ways in which one could be self-conscious. I conclude by addressing four objections to the possibility and reportability of totally selfless states of consciousness. (shrink)

Many authors claim that being conscious constitutively involves being self-conscious, or conscious of oneself. This claim appears to be threatened by reports of `selfless' episodes, or conscious episodes lacking self-consciousness, recently described in a number of pathological and nonpathological conditions. However, the credibility of these reports has in turn been challenged on the following grounds: remembering and reporting a past conscious episode as an episode that one went through is only possible if one was conscious of oneself while undergoing it. (...) Call this the Memory Challenge. This paper argues that the Memory Challenge fails to undermine the credibility to reports of selfless episodes, because it rests on problematic assumptions about episodic memory. The paper further argues that we should distinguish between several kinds of self-representation that may be involved in the process of episodic remembering, and that once we do so, it is no longer mysterious how one could accurately remember and report a selfless episode as an episode that one went through. Thus, we should take reports of this kind seriously, and view them as credible counter-examples to the claim that consciousness constitutively involves self-consciousness. (shrink)

All spaces are assumed to be separable and metrizable. We show that, assuming the Axiom of Determinacy, every zero-dimensional homogeneous space is strongly homogeneous (i.e. all its non-empty clopen subspaces are homeomorphic), with the trivial exception of locally compact spaces. In fact, we obtain a more general result on the uniqueness of zero-dimensional homogeneous spaces which generate a given Wadge class. This extends work of van Engelen (who obtained the corresponding results for Borel spaces), complements a result of van Douwen, (...) and gives partial answers to questions of Terada and Medvedev. (shrink)

This special issue is about something most of us might find very hard to conceive: states of consciousness in which self-consciousness is radically disrupted or altogether missing.

D. D. Raphael examines the moral philosophy of Adam Smith (1723-90), best known for his famous work on economics, The Wealth of Nations, and shows that his thought still has much to offer philosophers today. Raphael gives particular attention to Smith's original theory of conscience, with its emphasis on the role of 'sympathy' (shared feelings).

"Raphaël Debailiac est diplômé de la Sorbonne en philosophie et histoire.